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Biomarkar data analysis to find out patients of lung and head and neck cancer who responded to treatment and who did not respond to treatment

Identifying responder/non-responder status prior to anti-PD L1 or neo adjuvant/ palliative chemotherapy in Lung and Head and Neck cancers using a novel bioinformatic approach to analyze biomarker data. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/03/063428
Enrollment
360
Registered
2024-03-01
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx Health Condition 2: C349- Malignant neoplasm of unspecifiedpart of bronchus or lung

Interventions

Intervention1: NA: NA Control Intervention1: NA: NA

Sponsors

Tata Memorial Centre
Lead Sponsor
Samrud Foundation for Health and Research
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1.Lung (NSCLC) and oral (OSCC) cancer patients (Histo-pathologically diagnosed) who are slated to undergo anti-PD L1/ neoadjuvant or palliative chemotherapy. 2.Patients can provide sufficient tissues/blood for molecular analysis. 3.Consent from patients for utilization of their tissues and blood for this study.

Exclusion criteria

Exclusion criteria: 1.Pregnant women and patients under the age of 18 2.Those who are unfit to provide biopsy samples as per protocol 3.Those who refuse to consent to tissues being provided for research as per this protocol

Design outcomes

Primary

MeasureTime frame
1.To develop a method to predict response to anti-PDL 1/ neoadjuvant/ palliative chemo therapy in lung and oral cancer patients. 2.to confirm/ validate/ improve the method to predict response to anti-PDL 1/ palliative/ neoadjuvant chemo therapy in lung and oral cancer patientsTimepoint: At the end of study—

Secondary

MeasureTime frame
NaTimepoint: NA—

Countries

India

Contacts

Public ContactDr Kumar Prabhash

Tata Memorial Hospital

kprabhash1@gmail.com02224177214

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026