A study to do comparison between two drugs bupivacaine 0.5% ( Heavy ) with clonidine and ropivacaine 0.75% ( Heavy ) with clonidine in surgeries involving lower parts of the body by giving spinal anaesthesia

Comparative study of subarachnoid block with 0.75% hyperbaric ropivacaine plus clonidine versus 0.5% hyperbaric bupivacaine plus clonidine in surgeries of lower limbs and lower abdomen - Nil

Status

Recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/063415

Enrollment

Registered

2024-03-01

Start date

Unknown

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 3- Administration

Interventions

Intervention1: 0.5% Hyperbaric Bupivacaine Plus Clonidine: 3 ml of 0.5% Hyperbaric Bupivacaine Plus 45 micrograms Clonidine Single Injection via Spinal Anaesthesia Intervention2: 0.75% Hyperbaric Ropi

Eligibility

Inclusion criteria

Inclusion criteria: Any patients belongs to ASA grade I and II scheduled to undergo any major surgeries involving lower limbs and lower abdomen

Exclusion criteria

Exclusion criteria: ASA grade III and IV BMI more and equal to 30 General contraindications to spinal anaesthesia

Design outcomes

Primary

Measure	Time frame
Severity of Pain assessment using VAS pain scoreTimepoint: Intra-operatively every 30 minutes till the duration of surgery Post-operatively at 2, 4, 6, 8 and 12 hours	—

Secondary

Measure	Time frame
1. Total requirement of Injection Tramadol 2. Hemodynamic changes 3. Post operative complications ( nausea, vomiting, hypotension, sedation ) 4. Patient Satisfaction ScoreTimepoint: First 12 hours postoperatively	—

Countries

India

Contacts

Public ContactBharti

SGT University

dattvishnu@yahoo.com9718599406

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026