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A study to compare the safety and effectiveness of topical ozenoxacin vs mupirocin vs fusidic acid in impetigo contagiosa in pediatric age group.

An open label randomised controlled study to determine the efficacy and safety of topical Ozenoxacin vs Mupirocin vs Fusidic acid in mild to moderate impetigo contagiosa in pediatric age group. - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/03/063414
Enrollment
90
Registered
2024-03-01
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L010- Impetigo

Interventions

Intervention1: Ozenoxacin ,Fusidic Acid: Ozenoxacin 1% local application two times daily for seven days and Fusidic Acid 2% local application three times daily for seven days. Control Intervention1:

Sponsors

Ranjan Rashmiraj Sahu
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with clinical diagnosis of primary Impetigo. 2. Impetigo of mild( 3. Total affected area at baseline not exceeding 100 cm2 or more than 2% of the BSA. 4. Age between 2 month to 15 years. 5. Skin infection rating score more than equal to four. 6. Parent or legal guardian willing to comply with the protocol.

Exclusion criteria

Exclusion criteria: 1.Patient age less than 2 month and more than 15 years. 2.Impetigo of severe( >20 lesions)variety and which warrants systemic therapy. 3.Hypersensitivity to fusidic acid,mupirocin and ozenoxacin. 4.Pre existing eczematous dermatitis with clinical evidence of secondary infection or the presence of a bacterial infection that could not be appropriately treated by a topical antibiotic. 5.use of topical or systemic antibiotic or corticosteroids within one week of baseline.

Design outcomes

Primary

MeasureTime frame
Skin Infection Rating ScaleTimepoint: On 14th day

Secondary

MeasureTime frame
Skin Infection Rating ScaleTimepoint: 7th day

Countries

India

Contacts

Public ContactDr Swapnarani Behera

SCB medical college & hospital,Cuttack

dr.swapnaranibehera@yahoo.com9861148579

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026