Comparison of three techniques of giving oxygen during flexible bronchoscopy in children

Comparison of three methods of oxygen supplementation during flexible bronchoscopy in children: A randomized controlled trial - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/063406

Enrollment

177

Registered

2024-03-01

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J988- Other specified respiratory disorders

Interventions

Intervention1: Intervention 1: Oxygen supplementation through high flow nasal cannula (HFNC): The total duration of the procedure will be 10 to 20 minutes. The preparation of the child will be done ov

Eligibility

Inclusion criteria

Inclusion criteria: 1. Children 1 month – 15 years of age. 2. Undergoing elective flexible bronchoscopy examination for any indication

Exclusion criteria

Exclusion criteria: 1. The need for pre ?flexible bronchoscopy HFNC, noninvasive ventilation (NIV), or invasive mechanical ventilation (IMV) 2. Flexible bronchoscopy being performed as an emergency procedure. 3. Children on tracheostomy 4. Children with cyanotic heart disease 5. Children undergoing flexible bronchoscopy for endobronchial interventions apart from bronchoscopy and BAL.

Design outcomes

Primary

Measure	Time frame
Incidence of desaturations in children undergoing Flexible bronchoscopy while supplementing oxygen with modified nasopharyngeal insufflation and HFNC compared to nasal cannula in the age group of one month to fifteen yearsTimepoint: Saturation thirty minutes prior to procedure, saturation continuous monitoring during procedure, every 15 minute post procedure for two hours	—

Secondary

Measure	Time frame
Adverse events associated with the procedure, Major - post procedure oxygen requirement, intubation & mechanical ventilation, mortality, minor- nasopharyngeal bleeding or feverTimepoint: continuous monitoring during procedure, every 15 minute post procedure for two hours;Heart rate during the procedureTimepoint: Saturation thirty minutes continuous monitoring during procedure, every 15 minute post procedure for two hours;Number of patients requiring assisted breathing by bag & mask or Soong’s ventilationTimepoint: saturation continuous monitoring during procedure, every 15 minute post procedure for two hours . Number of patients requiring assisted breathing, If oxygen saturation less than eighty five percentage, or bradycardia, less than beats per min) for more than five seconds, the bronchoscopy will be interrupted & assisted ventilation will be started;Number of procedure interruptions or abandonmentTimepoint: during procedure, every 15 minute post procedure for two hours;Proportion of patients with desaturation less than Ninety percentTimepoint: Saturation thirty minutes prior to procedure, saturation continuous monitoring during procedure, every 15 minute post procedure for two hours;The lowest oxygen saturation during the procedure.Timepoint: saturation continuous monitoring during procedure, every 15 minute post procedure for two hours;The total duration of desaturations to less than Ninety percent & less than Ninety four percentTimepoint: Continuous monitoring during procedure, every 15 minute post procedure for two hours	—

Measure

Time frame

Adverse events associated with the procedure, Major - post procedure oxygen requirement, intubation & mechanical ventilation, mortality, minor- nasopharyngeal bleeding or feverTimepoint: continuous monitoring during procedure, every 15 minute post procedure for two hours;Heart rate during the procedureTimepoint: Saturation thirty minutes continuous monitoring during procedure, every 15 minute post procedure for two hours;Number of patients requiring assisted breathing by bag & mask or Soong’s ventilationTimepoint: saturation continuous monitoring during procedure, every 15 minute post procedure for two hours . Number of patients requiring assisted breathing, If oxygen saturation less than eighty five percentage, or bradycardia, less than beats per min) for more than five seconds, the bronchoscopy will be interrupted & assisted ventilation will be started;Number of procedure interruptions or abandonmentTimepoint: during procedure, every 15 minute post procedure for two hours;Proportion of patients with desaturation less than Ninety percentTimepoint: Saturation thirty minutes prior to procedure, saturation continuous monitoring during procedure, every 15 minute post procedure for two hours;The lowest oxygen saturation during the procedure.Timepoint: saturation continuous monitoring during procedure, every 15 minute post procedure for two hours;The total duration of desaturations to less than Ninety percent & less than Ninety four percentTimepoint: Continuous monitoring during procedure, every 15 minute post procedure for two hours

—

Countries

India

Contacts

Public ContactDr Kana Ram Jat

AIIMS New Delhi

drkanaram@gmail.com9868152426

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026