Efficacy Of Prophylactic Intravenous Administration Of Ondansetron For Prevention Of Spinal Anaesthesia Induced Hypotension.

A Comparative Study Of Prophylactic Intravenous Ondansetron On Spinal Anaesthesia Induced Hypotension Versus Placebo. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/063398

Enrollment

Registered

2024-03-01

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: INJECTION ONDANSETRON: The study population is divided into two groups of 38 each .Inj. ondansetron 4 mg diluted in 10 ml of NS for Group B while 10 ml of normal saline will be prepared

Eligibility

Inclusion criteria

Inclusion criteria: 1) Any patient going for non-obstetric surgery under spinal anesthesia 2) American Society of Anesthesiologists (ASA) Grade I or II 3) BMI 18.5-24.9kg/m2

Exclusion criteria

Exclusion criteria: 1. Patient refusal 2. Pregnant patients. 3. Any contraindication of spinal anesthesia. 4. Any spinal deformity. 5. Any patient with known hypersensitivity to ondansetron 6. Patients with comorbidities like diabetes, hypertension, asthma, tuberculosis. 7. Patients with conduction block. 8. Patient converted to general anesthesia

Design outcomes

Primary

Measure	Time frame
1)To study the effect of ondansetron for prevention of spinal anesthesia induced hypotension.Timepoint: Till 60 mins post operatively.	—

Secondary

Measure	Time frame
1) To evaluate the beneficial effects of ondansetron. 2) To study the advantage of pre loading in patients going for surgery under spinal anesthesia. 3) To determine the adverse effects of ondansetron if any.Timepoint: Till 60 mins post operatively.	—

Countries

India

Contacts

Public ContactDr Ajay Kumar Sinha

Government Medical College,Haldwani

sinhaak1961@gmail.com9897672301

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026