FindTrial
Sign In

Comparison of different doses of morphine given in spinal space in donor liver retrieval surgery.

Effect of different doses of intrathecal morphine on postoperative fentanyl consumption in open live donor hepatectomy- a double blind randomized control trial - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/02/063394
Enrollment
90
Registered
2024-02-29
Start date
Unknown
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Morphine: Intra thecal morphine either of the two different doses of 200 microgram or 400 micrograms before induction of general anesthesia in voluntary Healthy liver donor undergoing O

Sponsors

Suraj Deepak Desai
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Voluntary Healthy liver donors undergoing Open Live Donor Hepatectomy

Exclusion criteria

Exclusion criteria: 1. Patient refusal 2.Contraindication to neuraxial anaesthesia 3.Allergy to morphine 4. History of drug abuse 5.Insufficient comprehension to use of patient controlled analgesia (PCA)

Design outcomes

Primary

MeasureTime frame
To compare total postoperative fentanyl consumption at 24 hours between the three different doses of intrathecal morphine in patients undergoing open live donor hepatectomyTimepoint: 24 hours post open live donor hepatectomy—

Secondary

MeasureTime frame
1.To compare total postoperative fentanyl consumption at 72 hours 2.To compare postoperative static VAS score at 0, 2, 4, 12, 24, 36, 48 & 72 hours 3.To compare postoperative dynamic VAS score at 0, 2, 4, 12, 24, 36, 48 & 72 hours 4.To compare the sedation score at 0, 2, 4, 12, 24, 36, 48 & 72 hours 5.To compare the incidence of PONV, pruritus, delayed respiratory depression between the different groups. 6.Time to pass the first stools after surgery 7.Time of first rescue analgesic 8. Time to mobilize Timepoint: At 2, 4,12,24,36,48 & 72 hours post open live donor hepatectomy—

Countries

India

Contacts

Public ContactSuraj Deepak Desai

Institute of liver and biliary sciences

drsindwani25@gmail.com8728089898

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026