Comparison of 2 methods for treatment of missing gums in between teeth.

Comparative evaluation of two minimally invasive techniques for the treatment of interdental papillary reconstruction using injectable PRF and 5%Hyaluronic acid gel-A Randomized controlled clinical trial - Nil

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/02/063384

Enrollment

Registered

2024-02-29

Start date

Unknown

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Injection of i-PRF: The patient’s blood sample is drawn in i-PRF tube and immediately centrifuged at 700 rpm for 3 minutes, in centrifugation machine. The liquid form of i- PRF is taken

Eligibility

Inclusion criteria

Inclusion criteria: 1) Subjects who have agreed to be participate voluntarily. 2) Males and females in the age group of 25 - 45 years. 3) Subjects who have undergone periodontal flap surgery at least before three months. 4) Class 1 and 2 interdental papilla loss (Nordland and Tarnow 1998). 5) Subjects with history of compliance to oral hygiene instructions.

Exclusion criteria

Exclusion criteria: A history of Subjects with known allergy to hyaluronic acid Pregnant & lactating woman. Current Smokers.

Design outcomes

Primary

Measure	Time frame
1) To assess the gain in papilla height after application of i-PRF in maxillary and mandibular IDP deficiencies from baseline to one month and four months. 2) To assess the gain in papilla height after application of injectable 5% Hyaluronic acid gel in maxillary and mandibular IDP deficiencies from baseline to one month and four months. Timepoint: Outcome assesments will be made at 3 timepoints during the study period. At Baseline, 1 month and 4 months.	—

Measure

Time frame

1) To assess the gain in papilla height after application of i-PRF in maxillary and mandibular IDP deficiencies from baseline to one month and four months. 2) To assess the gain in papilla height after application of injectable 5% Hyaluronic acid gel in maxillary and mandibular IDP deficiencies from baseline to one month and four months. Timepoint: Outcome assesments will be made at 3 timepoints during the study period. At Baseline, 1 month and 4 months.

—

Secondary

Measure	Time frame
To compare the gain in papilla height and clinical outcomes between the two groups, after application of iPRF and 5% Hyaluronic acid gel in maxillary and mandibular IDP deficiencies from baseline to one month and four months.Timepoint: one year six months	—

Countries

India

Contacts

Public ContactDr. Bindu D. R.

Dayananda Sagar College of Dental Sciences,Bangalore

archananaik@dscds.edu.in9986204322

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026