CO2 Laser vs Traditional Scalpel for surgical management of oral precancerous lesions

Comparative evaluation of CO2 Laser and traditional scalpel in the surgical management of oral potentially malignant disorder- A Randomized Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/02/063297

Enrollment

Registered

2024-02-29

Start date

Unknown

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K132- Leukoplakia and other disturbancesof oral epithelium, including tongue

Interventions

Intervention1: Co2 Laser: Use of Co2 laser for surgical management of oral potentially malignant disorder under necessary anaesthesia- surgery lasting upto maximum of 2 hours. Follow up taken till 2 w

Eligibility

Inclusion criteria

Inclusion criteria: 1. All the patients reporting to department with oral potentially malignant disorders 2. Patients of age 15 years and above and below 75 years 3. Patients fit to undergo surgical excision under necessary anaesthesia 4. Patients with controlled blood sugar level 5. Patients with good general health status

Exclusion criteria

Exclusion criteria: 1. Patients with systemic immunocompromised conditions 2. Patients who are pregnant/ lactating mothers 3. Patients on steroids or oral contraceptives 4. Patients not fit to undergo surgical excision under necessary anaesthesia 5. Patients not willing to be a part of the study

Design outcomes

Primary

Measure	Time frame
1.Post-operative pain 2.Post operative swelling/edema Timepoint: On the day of surgery, first and second week post operatively	—

Secondary

Measure	Time frame
Ease of operabilityTimepoint: On the day of surgery;Intraoperative bleedingTimepoint: On the day of surgery;Post-operative scarringTimepoint: First and second week post operatively	—

Countries

India

Contacts

Public ContactDr Vartik Shah

Government Dental College & Hospital, Nagpur

abhaydatarkar@yahoo.com9930014736

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026