Comparing the effectiveness of a topical gel containing hyaluronic acid and doxycycline with oral medications for accelerating wound healing after dental extractions.

Evaluate the comparision & formulation of a gel comprising hyaluronic acid & doxycycline hyclate in patients indicated for dental extractions: a prospective study - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/02/063277

Enrollment

Registered

2024-02-28

Start date

Unknown

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: A wound-healing gel with hyaluronic acid and doxycycline hyclate.: one time local intra socket placement of 1ml gel immediately after tooth extraction secured with sutures for 7 days Co

Eligibility

Inclusion criteria

Inclusion criteria: patients with chronic dental infection (chronic apical periodontitis) ASA category 1 patients patients without any other medications

Exclusion criteria

Exclusion criteria: patients with acute infection immunocompromised patients pregnant & lactating female patients patient currently on any other medication ASA category 2, 3, 4

Design outcomes

Primary

Measure	Time frame
To evaluate & compare the efficacy of local drug delivery of hyaluronic acid + doxycycline gel versus placebo gel with amoxicillin tablet orally in the management of wound healing after tooth extraction in patients with chronic infection Timepoint: baseline, 3rd day, 7th day, and 15th day	—

Secondary

Measure	Time frame
To eradicate the inflammation & to arrest the bacterial infection To reduce the level of TrismusTimepoint: baseline, 3rd day, 7th day	—

Countries

India

Contacts

Public ContactHarshavardhan Shelke

government dental college & hospital mumbai

dr.kavitawadde@gmail.com9004799405

Outcome results