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Examining the link between ultrasound measured eye nerve size and the timing of discontinuing magnesium sulphate treatment in pre-eclamptic patients with severe features – A preliminary observation study

To study the correlation between ultrasound guided optic nerve sheath diameter measurements with respect to timing of stopping of magnesium sulphate therapy, in pre-eclamptic patients with severe features – a prospective, observational, pilot study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/02/063264
Enrollment
30
Registered
2024-02-28
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O141- Severe pre-eclampsia

Interventions

Intervention1: NIL: NIL Control Intervention1: NIL: NIL Control Intervention2: NIL: NIL Control Intervention3: NIL: NIL

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Pregnant patients aged =18 years Period of gestation = 20 weeks Presenting with pre-eclampsia with severe features Patients who will receive MgSO4 therapy Planned for termination of pregnancy

Exclusion criteria

Exclusion criteria: Patient’s refusal Eclamptic patients Patient who receives MgSO4 prior to first reading of optic nerve sheath diameter. Patients who have undergone previous cranial or eye surgeries Patients suffering from seizures, intracranial or eye pathology, glaucoma or any other neurological condition. Patients with uncontrolled diabetes or cardiac disease

Design outcomes

Primary

MeasureTime frame
A high optic nerve sheath diameter value (= 5.8 mm) is expected in patients presenting with pre-eclampsia with severe features at various time points in the post natal period even after stopping of MgSO4 therapy.Timepoint: Ultrasound guided optic nerve sheath diameter assessment will be done prior to start of MgSO4 therapy and baseline value will be noted. Thereafter, ultrasound guided optic nerve sheath diameter assessment will be done at 6 hour time point after starting of MgSO4. Subsequent values will be noted immediately after delivery and thereafter at 12 hour, 24 hour and 48 hour time point after delivery.—

Secondary

MeasureTime frame
NILTimepoint: NIL—

Countries

India

Contacts

Public ContactDr Sarita Ramchandani

AIIMS, Raipur

drsaritaramchandani@gmail.com9424204244

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026