Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: NIL: NIL
Control Intervention1: NIL: NIL
Sponsors
None
Eligibility
Inclusion criteria
Inclusion criteria: 1 Diagnosis of supratentorial brain tumor by MRI or CT Brain 2 Undergoing elective craniotomy under general anesthesia
Exclusion criteria
Exclusion criteria: 1 Patient refusal to participate in study or refusal to follow up. 2 Patients with severe anemia (hb less than 7 g per L) 3 Neutropenia( less than 1000 million per L) or active infection( TLC more than 11000 million per L) 4 Active inflammatory, hematological, or autoimmune system disease history. 5 History of Chemotherapy or Radiotherapy or Immunomodulators in past 3 months. 6 Severe conditions involving the cardiac, hepatic or the renal system 7 Previous brain tumor surgery or treatment 8 History of drug abuse or anaphylaxis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess predictive value of preoperative Systemic Immune Inflammation Index for favourable prognosis as Karnofsky Performance Scale morethan or equal to eighty in patients undergoing craniotomy surgeries.Timepoint: At three months postoperatively | — |
Secondary
| Measure | Time frame |
|---|---|
| Analysis of preoperative SII in subgroups ie. Pediatric vs adults and benign vs malignantTimepoint: Preoperatively;Analysis of values of SII, NLR,PLR and LMRTimepoint: Preoperatively and postoperatively at 24hrs and 3rd day;Correlation of postoperative SII index with duration of surgeryTimepoint: At the end of surgery;Correlation of preoperative SII index with duration of ICU and hospital stayTimepoint: At discharge | — |
Countries
India
Contacts
Public ContactPriyanka Gupta
Aiims Rishikesh
Outcome results
None listed