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How Effective is Nebulization With 3% Hypertonic Saline Against 0.9% Normal Saline In Children With Viral Lung Infection.

Comparative Study of Nebulization With 3% Hypertonic Saline Versus 0.9% Normal Saline In Children With Acute Bronchiolitis - NIL

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/02/063234
Enrollment
58
Registered
2024-02-28
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J219- Acute bronchiolitis, unspecified

Interventions

Intervention1: Nebulization With 3% Hypertonic Saline: Nebulization With 4ml of 3% Hypertonic Saline In Children With Acute Bronchiolitis every two hourly for three doses, followed by every four hourl

Sponsors

E AJAYA KUMAR
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Previously healthy infants and children below 24 months of age admitted with first episode of respiratory tract infection with wheeze, starting as a viral upper respiratory infection (coryza, cough, fever), and a clinical severity score above 04.

Exclusion criteria

Exclusion criteria: Children with previous episode of wheezing, chronic cardio-pulmonary disease or immunodeficiency; critical illness at presentation requiring ventilator support; the use of nebulised HS within the previous 12 hours; or premature birth (gestational age 34 weeks), X Ray showing significant findings like consolidation patches, collapse lung, pleural effusion will be excluded from the study.

Design outcomes

Primary

MeasureTime frame
1.Time taken for improvement in CSS(Clinical Severity Score 2.Time taken for normalisation of Oxygen Saturation 3.Duration of Oxygen therapy 5.Duration of hospital stayTimepoint: Comparing data for outcomes at 6hour intervals

Secondary

MeasureTime frame
1.Comparing primary outcomes in relation to demographic profile of study subjects 2. Comparing primary outcomes in relation to duration of symptoms before admission, age & nutritional status of study subjectsTimepoint: At discharge of each patient

Countries

India

Contacts

Public ContactDr YOGENDRA SINGH VERMA

Gajra Raja Medical College, Gwalior

ysverma86@gmail.com9425112504

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026