Health Condition 1: G610- Guillain-Barre syndrome
Conditions
Interventions
Intervention1: THERAPEUTIC PLASMA EXCHANGE: first line treatment for patients of Guillain Barre Syndrome
frequency: 5 sessions over 10 days
total duration: 10 days
Control Intervention1: INTRAVENOUS I
Sponsors
SCB Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Clinically and electro physiologically diagnosed cases of GBS with The cases will be age and sex matched Both procedures are indicated
Exclusion criteria
Exclusion criteria: 1. Patients of GBS who have achieved plateau of GBS 2. Previous episodes of GBS 3. Pregnancy 4. Severe concurrent Medical illness like TB 5. Any one of these procedures contraindicated 6. Patients whose modality of treatment has been changed from IVIG to TPE or vice versa 7. Specific exclusions with atypical features such as- a. Purely sensory symptoms b. Cranial nerve palsies without significant limb weakness c. Improvement of one or more disability grades before inclusion
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A decrease in GBS Disability scale by 1 or more points at discharge as compared to the same at admissionTimepoint: Patient will be evaluated as per GBS disability score throughout the treatment period and up to 6 month | — |
Secondary
| Measure | Time frame |
|---|---|
| total cost of treatment in Indian RupeesTimepoint: from the day of admission to the day of discharge | — |
Countries
India
Contacts
Public ContactNilasish Pani
SCB Medical College and Hospital
Outcome results
None listed