A study evaluating the effect of rTMS in infertile women with moderate to severe depression

Does rTMS Repetitive transcranial magnetic stimulation improve the outcome of in vitro fertilization in infertile women with moderate to severe depression - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/02/063171

Enrollment

Registered

2024-02-26

Start date

Unknown

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N97- Female infertility Health Condition 2: F33- Major depressive disorder, recurrent Health Condition 3: F32- Major depressive disorder, singleepisode

Interventions

Intervention1: rTMS (Repetitive transcranial magnetic stimulation): Neuromodulation technique that uses a magnetic field to stimulate focal cortical brain regions with electrical currents given for 3

Eligibility

Inclusion criteria

Inclusion criteria: 1. Women undergoing IVF at ART center & willing to participate 2. Moderate to severe depression

Exclusion criteria

Exclusion criteria: Comorbid psychiatric illness Substance abuse including nicotine Any other contraindication for rTMS Women with moderate to severe depression opting for pharmacotherapy Donor Recipient cycles Severe OATS (Oligoasthenoteratozoospermia) Oncofertility Hyper-responders like PCOS undergoing segmented Embryo Transfer

Design outcomes

Primary

Measure	Time frame
Effect of rTMS on the clinical pregnancy rate in infertile women with depression undergoing IVF-Fresh ETTimepoint: 8 weeks	—

Secondary

Measure	Time frame
Implantation success by measuring Beta HCG levelsTimepoint: 7 weeks;Oocyte and Embryo qualityTimepoint: 6 weeks;To assess depression measured using HAM-D questionnaire pre and post rTMSTimepoint: 3 weeks;To assess the biochemical levels (Cortisol, BDNF) pre and post rTMSTimepoint: 3 weeks	—

Countries

India

Contacts

Public ContactDr Kataru Nikitha

AIIMS, New Delhi

drneetasingh@yahoo.com9818506855

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026