A clinical trial to study the effect of Oral Laser Light vs. Medication in Treating oral lichen planus which is a disease that causes burning sensation in mouth.

Comparison of the Efficacy of Photodynamic Therapy (Methylene blue using Soft Tissue Diode LASER) with Topical Tacrolimus in the Management of patients with Oral Lichen planus- Two arm double blinded clinical trial. - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/02/063136

Enrollment

Registered

2024-02-26

Start date

Unknown

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K137- Other and unspecified lesions of oral mucosa

Interventions

Intervention1: To compare the efficacy of photodynamic therapy using Methylene blue dye and soft tissue diode LASER with topical tacrolimus in the management of patients with oral lichen planus. : Co

Eligibility

Inclusion criteria

Inclusion criteria: clinically and histopathologically cofirmed cases of lichen planus, patients who have cleared the patch test for tacrollimus participants wiiling to be part of the study and have signed informed consent

Exclusion criteria

Exclusion criteria: patients having other autoimmune disorders. patients who are already under going gtreatment for lichen planus. pregnant and lactating women. patient with allergies to methyllene blue,tacrollimus,LASERS

Design outcomes

Primary

Measure	Time frame
Independent variables- Tacrolimus, Photodynamic therapy Dependent variables-burning sensation,pain,size of lesionTimepoint: 8 weeks	—

Secondary

Measure	Time frame
Dependent variables - Dependent variable-Burning sensation, pain, size of the lesion Independent variables- Tacrolimus, Photodynamic therapy Timepoint: 12 weeks	—

Countries

India

Contacts

Public ContactDr Annette Bhambal

Peoples college of Dental sciences and Research centre,Bhopal,M.p

drabhambal@gmail.com9826088574

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026