Health Condition 1: M179- Osteoarthritis of knee, unspecified Health Condition 2: N400- Benign prostatic hyperplasia without lower urinary tract symptoms Health Condition 3: M169- Osteoarthritis of hip, unspecified
Conditions
Interventions
Intervention1: Use of Norepinephrine (8mcg) intravenous bolus.: Use of Norepinephrine (8mcg) intravenous bolus just after intrathecal drug administration, which will be repeated in case of hypotension
Sponsors
All India Institute of Medical Sciences Sijua Patrapada Bhubaneswar, Odisha India
Eligibility
Inclusion criteria
Inclusion criteria: ASA I/II patients of age = 60 years undergoing surgery using spinal anesthesia.
Exclusion criteria
Exclusion criteria: Patients with known cardiac abnormalities, Use of Mono Amine Oxidase inhibitor, Patients with known allergy to the study drugs, Patients with contraindications for SAB, Patient refusal for consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effect of bolus norepinephrine vs phenylephrine on the incidence of bradycardia in elderly patients under spinal anesthesia.Timepoint: first 24 hours postoperatively | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To compare the number of episodes of hypotension and the time of the first episode of hypotension 2. To compare the intraoperative use of norepinephrine, phenylephrine, ephedrine, atropine and fluids 3. To compare the changes in the Flow time corrected (FTc) (preoperative, 5min after spinal anesthesia, and immediately after surgery in PACU) 4. To compare the episodes of reactive hypertension and postoperative complications within first 24hrs. Timepoint: first 24 hours postoperatively | — |
Countries
India
Contacts
Public ContactDr J Sharath Chandra Reddy
All India Institute of Medical Sciences, Bhubaneswar
Outcome results
None listed