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Impact of laparoscopic sleeve gastrectomy surgery on vasoactive mediators in morbid obese patients.

Impact of Laparoscopic Sleeve Gastrectomy on vasoactive mediators in patients with morbid obesity. - Nil

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/02/063079
Enrollment
30
Registered
2024-02-23
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E669- Obesity, unspecified

Interventions

Intervention1: Laparoscopic sleeve gastrectomy surgery: Surgery done after patient preparation, and pre-op and 3months post-op serum levels of vasoactive mediators are compared Control Intervention1:

Sponsors

LADY HARDINGE MEDICAL COLLEGE
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Morbidly Obese individuals with BMI more than 37.5; Morbidly Obese individuals with BMI more than 32.5 with comorbidities like hypertension, diabetes mellitus, hypercholesterolemia, non alcoholic fatty liver disease, cardiovascular disease.

Exclusion criteria

Exclusion criteria: History of cerebrovascular accident in last 6 months. Known case of Severe hepatic, cardiac, psychiatric diseases Known case of Renal artery stenosis and renal disorders. Patients lost to follow up.

Design outcomes

Primary

MeasureTime frame
Change in serum levels of angiotensinogen, renin, aldosterone, and free fatty acids 3 months after laparoscopic sleeve gastrectomy.Timepoint: Before and 3 months after surgery.

Secondary

MeasureTime frame
1.To calculate the percentage excess weight loss 3 months after laparoscopic sleeve gastrectomy. 2.To correlate the percentage excess weight loss with the change in serum levels of angiotensinogen, renin, aldosterone and free fatty acids 3 months after laparoscopic sleeve gastrectomy.Timepoint: Before and 3 months after surgery.

Countries

India

Contacts

Public ContactSUMANTHAREDDY B H

Lady Hardinge Medical College

mandley@hotmail.com9312345379

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026