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Effect of gaseous anaesthesia agents on the delivery of oxygen and the oxygen content at various interval and on the heart rate, blood pressure and oxygen content of the blood during the process of oxygenating a patient before putting a tube for assisting breathing during surgery.

Effect of inhalational agents on pre-intubation oxygenation and hemodynamic parameters:A randomized, single blind, pilot study. - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/02/063076
Enrollment
96
Registered
2024-02-23
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Use of inhalational agents during pre-intubation oxygenation.: Group A: Patients who will receive inhalational anaesthetic isoflurane set at a dial concentration of 1% during pre-intuba

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Age: adults aged between 18 – 60 years 2.Gender: Male and female 3.Volatile anaesthesia with the use of Muscle relaxants 4.Elective Surgery 5.ASA-PS I-III 6. BMI 18.5-29.9 Kg/m2

Exclusion criteria

Exclusion criteria: 1.Patient refusal 2.Pregnant women 3.Improper fit of oronasal mask, anticipated and unanticipated difficult mask ventilation 4.Undergoing Rapid Sequence Intubation 5.Patients with significant cardio-respiratory disease like Coronary artery disease, Stroke, Peripheral vascular disease, Aortic disease, Deep vein thrombosis, Heart failure, COPD, Pneumonia, Asthma, Cystic fibrosis etc

Design outcomes

Primary

MeasureTime frame
the addition of inhalational anaesthetic will affect pre intubation oxygenation negatively, but hemodynamic parameters like heart rate,blood pressure, oxygen saturation will not be affected much.Timepoint: 5 minutes

Secondary

MeasureTime frame
nilTimepoint: nil

Countries

India

Contacts

Public ContactDr Nandkishore Agrawal

AIIMS, Raipur

nkagrawal1963@gmail.com9373103294

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026