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Multiple sectioning of lymph node to look for micro metastasis and extension of tumor beyond lymph node capsule

step serial sectioning of lymph node in oral squamous cell carcinoma for micrometastasis and extranodal extension:A cross sectional study - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/02/063074
Enrollment
40
Registered
2024-02-23
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx Health Condition 2: C068- Malignant neoplasm of overlappingsites of other and unspecified parts of mouth

Interventions

Control Intervention1: Nil: Nil

Sponsors

Mahima jaiswal
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All histopathologically diagnosed cases of oral squamous cell carcinoma undergoing radical neck dissection and showing: Node negative(NO) on pN staging pN stage N1-N3 with ENE negative status.

Exclusion criteria

Exclusion criteria: • Cases showing both nodal positivity and ENE positivity on H&E staining. • Cases of oral squamous cell carcinoma who have undergone pre-operative chemotherapy and radiotherapy. • Cases with recurrence of disease. • Cases with any concurrent malignancy.

Design outcomes

Primary

MeasureTime frame
To classify oral squamous cell carcinomas based on pathological tumor(pT) and nodal stage(pN) To determine the percentage increased nodal positivity in the node negative (NO) cases of radical neck dissection of oral squamous cell carcinoma on applying step serial sectioning. To calculate the percentage of increased ENE positive status in cases of ENE negative and nodal positive squamous cell carcinoma with use of step serial sectioning.Timepoint: 4 weeks

Secondary

MeasureTime frame
To classify oral squamous cell carcinomas based on pathological tumor(pT) & nodal stage(pN) To determine the percentage increased nodal positivity in the node negative (NO) cases of radical neck dissection of oral squamous cell carcinoma on applying step serial sectioning. • To calculate the percentage of increased ENE positive status in cases of ENE negative & nodal positive squamous cell carcinoma with use of step serial sectioning.Timepoint: 4 weeks

Countries

India

Contacts

Public ContactMahima jaiswal

Rohilkhand Medical college and hospital

dr.mithila@gmail.com7906080213

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026