Health Condition 1: J869- Pyothorax without fistula
Conditions
Interventions
Intervention1: Saline Irrigation of the pleura: Large volume saline irrigation via chest tube three times a day
Control Intervention1: Standard of care to keep the chest tube patent: Standard Flushing
Sponsors
Dr Shakti Kumar Bal
Dr Siddarth Singh
Eligibility
Inclusion criteria
Inclusion criteria: adults male and female with complicated parapneumonic pleural effusion complicated parapneumonic pleural effusion defined as pleural effusion that is macroscopically purulent, or positive on routine aerobic culture or positive on gram stain or positive AFB/CBNAAT or pleural fluid that has pH less than 7.2 or pleural fluid that has glucose less than 72mg/dl or pleural fluid LDH more than 900 IU/L or loculated pleural effusion
Exclusion criteria
Exclusion criteria: Age less than 15 years or previous thoracic surgery or chest tube insertion done more than 72 hours ago or chest tube size more than 16 french or drainage not safe due to organised pleural effusion or fluid not amenable to safe intervention or pregnancy or infected malignant pleural effusion or presence of air leak more than grade 2
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Proportions of patient needing surgery at 30 days in each armTimepoint: Baseline, day 3, day 7, day 14, and day 30. | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical and radiological improvement at the end of interventionTimepoint: 30 days;Length of Hospital StayTimepoint: 30 days;Change in the clinical fraility index, Fi-LAB and RAPID score at end of 1 monthTimepoint: 30 days;Reduction in inflammatory markers- CRP, neutrophilic Leucocytosis at end of treatmentTimepoint: 30 days;Additional pleural manoeuvres required like additional chest drain or additionall thoracoscopyTimepoint: 30 days | — |
Countries
India
Contacts
Public ContactDr Siddarth Singh
All India Institute of Medical Sciences, Bhubaneswar
Outcome results
None listed