To compare the antimicrobial efficacy of liquorice and chlorhexidine (1%) gel as cavity disinfectants in deciduous molars

“A Randomized Controlled Trial to Compare the Antimicrobial Efficacy of Licorice and CHLORHEXIDINE (1%) GEL as cavity disinfectants in deciduous molars ? - nil

Status

Active, not recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/02/063000

Enrollment

Registered

2024-02-21

Start date

Unknown

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K02- Dental caries Health Condition 2: K029- Dental caries, unspecified

Interventions

Intervention1: Group 1- CHLORHEXIDINE GLUCONATE (1%): 1% chlorhexidine Di gluconate which is commercially available as Hexigel. will be applied at the baseline and for 1 minute. Total duration of ap

Eligibility

Inclusion criteria

Inclusion criteria: Children with deep dentinal carious deciduous teeth with no symptoms, signs and radiographic findings pertained to irreversible pulpitis( abscess, fistula, sinus) were selected.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
a study is planned to evaluate and compare the antimicrobial effectiveness of Liquorice (Mulethi) and Chlorhexidine (1%) gel in children aged 5 to 9 years old as cavity disinfectants.Timepoint: Liquorice (Mulethi) and Chlorhexidine (1%) gel in children and normal saline are applied as baseline and 1 minute after application the samples will be taken.	—

Secondary

Measure	Time frame
1. To evaluate & comparison of the antimicrobial efficiency of pre & post-application of liquorice as cavity disinfectant. 2. To evaluate & comparison of the antimicrobial efficiency of pre & post-application of chlorhexidine (1%) gel as cavity disinfectant. 3. To evaluate & comparison of the antimicrobial efficiency of post-liquorice & post-chlorhexidine (1%) gel as cavity disinfectant. 4. To evaluate & comparison of the antimicrobial efficiency of post-liquorice & post-chlorhexidine (1%) gel with saline (control) as cavity disinfectants. Timepoint: liquorice, chlorhexidine gel & normal saline samples will be taken at baseline & 1 minute after application of agents	—

Measure

Time frame

1. To evaluate & comparison of the antimicrobial efficiency of pre & post-application of liquorice as cavity disinfectant. 2. To evaluate & comparison of the antimicrobial efficiency of pre & post-application of chlorhexidine (1%) gel as cavity disinfectant. 3. To evaluate & comparison of the antimicrobial efficiency of post-liquorice & post-chlorhexidine (1%) gel as cavity disinfectant. 4. To evaluate & comparison of the antimicrobial efficiency of post-liquorice & post-chlorhexidine (1%) gel with saline (control) as cavity disinfectants. Timepoint: liquorice, chlorhexidine gel & normal saline samples will be taken at baseline & 1 minute after application of agents

—

Countries

India

Contacts

Public ContactBhavna gupta saraf

Sudha rustagi college of dental science and research faridabad

guptabhavna2000@yahoo.com9899124779

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026