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Symptomatic outcome of pancreatic enzyme replacement therapy in cases of pancreatic exocrine insufficiency

Outcome of post pancreatic enzyme replacement therapy in patients of pancreatic exocrine insufficiency - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/02/062996
Enrollment
40
Registered
2024-02-21
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: nil: nil

Sponsors

Dr Somya Goel
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Clinically confirmed case of acute and chronic pancreatitis with exocrine insufficiency in patients above 18 years of age Patients with Baltahazar CT severity index of 2 and more

Exclusion criteria

Exclusion criteria: Other pancreatic pathology like pancreatic malignancy, cyst. Contraindicated cases for contrast ct study. Patients where quality of life cannot be assessed

Design outcomes

Primary

MeasureTime frame
Assess reduction in pain, bloating and sticky stool and weight changes post pancreatic enzyme replacement therapy in patients of pancreatic exocrine insufficiency Timepoint: 0 days 15 days 45 days

Secondary

MeasureTime frame
Grading of complaints of pain on the basis of ‘visual analogue scale’ Grading of CT scan findings based on Baltahazar CT severity index Documentation of weight changes pre and post therapy using same standard weighing scale . General improvement in clinical symptoms and lifestyle changes will be assessed through WHO quality of life scale Regular follow up at 0 days – 15 days – 45 days to check compliance towards therapy will be done first hand using Morisky Medication Adherence Scale (MMAS-8) Timepoint: 16 MONTHS TO 34 MONTHS

Countries

India

Contacts

Public ContactDr RK SHINDE

Jawaharlal Nehru Medical College, Sawangi(Meghe), Wardha

raju.shinde95@gmail.com8087148087

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026