The study to compare two different dose of norepinephrine based on weight of the patient for preventing fall in blood pressure after spinal anaesthesia in patients undergoing cesarean section

Randomised double blind study of comparing two weight adjusted doses of norepinephrine for preventing hypotension during spinal anaesthesia for elective Caesarean section - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/02/062991

Enrollment

170

Registered

2024-02-21

Start date

Unknown

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O00-O9A- Pregnancy, childbirth and the puerperium

Interventions

Intervention1: Norepinephrine infusion for preventing hypotension in elective lower segment cesarean section: weight adjusted dose of norepinephrine infusion at concentration of 0.05mcg//kg/min . And

Eligibility

Inclusion criteria

Inclusion criteria: 1)full term women undergoing elective cesarean section 2) ASA class II 3)age between 18-35 years

Exclusion criteria

Exclusion criteria: 1) patients refusal 2)hypertensive disorders 3)cardiac diseases 4)allergy to local anaesthetics 5)obstretic complications (antepartum hemorrhage,placenta privea,placental abruption) 6)coagulopathy,sepsis,hepatic or renal failure

Design outcomes

Primary

Measure	Time frame
1)Doses of rescue bolus of phenylephrine 20 mcg 2)access incidence of hypotension in both groupsTimepoint: Incidence of hypotension is assessed immediately after spinal anaesthesia measurement of blood pressure every 1 minute after spinal till the delivery of baby and the amount of PHENYLEPHERINE boluses used during the intraoperative period.	—

Secondary

Measure	Time frame
1)intraoperative blood pressure(systolic and diastolic h Pressure) 2)mean arterial pressure 3)post operative shiveringTimepoint: 1)intraoperative blood pressure at baseline and 1minute after spinal anaesthesia till end of the procedure 2)post operative shivering accessed after giving spinal anaesthesia and in the post anaesthetic care unit 3)mean arterial pressure at baseline and 1 minute after giving spinal anaesthesia till the end of procedure	—

Measure

Time frame

1)intraoperative blood pressure(systolic and diastolic h Pressure) 2)mean arterial pressure 3)post operative shiveringTimepoint: 1)intraoperative blood pressure at baseline and 1minute after spinal anaesthesia till end of the procedure 2)post operative shivering accessed after giving spinal anaesthesia and in the post anaesthetic care unit 3)mean arterial pressure at baseline and 1 minute after giving spinal anaesthesia till the end of procedure

—

Countries

India

Contacts

Public ContactSK SAIF ALI

SRI Ramachandra institute of higher education and research

reetharun@gmail.com9840529863

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026