Health Condition 1: E119- Type 2 diabetes mellitus without complications
Conditions
Interventions
Intervention1: Pioglitazone: 30 mg BIW for 3 months
Control Intervention1: Pioglitazone
: 7.5 mg OD for 3 months
Sponsors
Dr Deepak Anand R
Dr Thivyahprabha A G
Eligibility
Inclusion criteria
Inclusion criteria: HbA1C more than 7.0 % FBS more than 126 mg/dl RBS more than 200 mg/dl Any duration of Diabetes Mellitus On oral antidiabetics or naive to medications BMI between 18 and 35 kg/cm
Exclusion criteria
Exclusion criteria: On insulin treatment or be initiated during study period Patients on pioglitazone or have received pioglitazone in the last one year Past H/O Hematuria Liver enzymes more than 2.5 ULN at baseline eGFR less than 60mg/dl Concomitant CAD and/or Heart Failure Pedal edema of any cause On Digoxin, Warfarin, Oral Contraceptives Females of childbearing potential Pregnant females & Nursing Mother Presence of proliferative diabetic retinopathy Patients who have not given consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Decreased Insulin Resistance and Improved Glycemic ControlTimepoint: Baseline 4 weeks and 8 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Improved Lipid ProfileTimepoint: Baseline, 4 weeks and 12 weeks | — |
Countries
India
Contacts
Public ContactDr Deepak Anand R
St Peters Medical College Hospital
Outcome results
None listed