Health Condition 1: M051- Rheumatoid lung disease with rheumatoid arthritis
Conditions
Interventions
Control Intervention1: NIL: NIL
Sponsors
The Executive Director, All India Institute of Medical Sciences, Rajkot
Eligibility
Inclusion criteria
Inclusion criteria: Patients with Rheumatoid arthritis having pulmonary complications. (diagnosis will be based on ACR/EULAR criteria using clinical history, examination, immunological investigation, radiological investigations) Healthy age and gender matched volunteers without any pulmonary disease, systemic illness or connective tissue disorders.
Exclusion criteria
Exclusion criteria: Patients with pulmonary manifestations which are not attributable to Rheumatoid arthritis. Refusal of consent for participation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Identification of difference in profile of circulatory H3 with various epigenetic modifications in patients with rheumatoid arthritis with pulmonary complications.Timepoint: 0-6 months: Method standardization 7-22 months: Subject recruitment & biochemical analysis of serum samples. 22-24 months: Statistical analysis | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation of therapeutic response of ongoing treatment and epigenetic profile of circulatory H3 modifications.Timepoint: 0-6 months: Method standardization 7-24 months: Subject recruitment, biochemical analysis of serum samples & find out correlation between therapeutic response of ongoing treatment and epigenetic profile of circulatory H3 modifications. | — |
Countries
India
Contacts
Public ContactDr Amit D Sonagra
All India Institute of Medical Sciences, Rajkot
Outcome results
None listed