To compare post operative pain relief using drugs dexmedetomidine and fentanyl added to bupivacaine in lower abdominal surgery.

A comparative study of post operative analgesia using intra thecal Dexmedetomidine and fentanyl as adjuvant to bupivacaine in lower abdominal surgeries. A Randomized double blinded study - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/02/062910

Enrollment

Registered

2024-02-20

Start date

Unknown

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Dexmedetomidine and fentanyl: Group A- will receive 2 ml 0.5% hyperbaric bupivacaine + 0.2 ml (12.5µgm) Fentanyl citrate. Group B- will receive 2 ml 0.5% hyperbaric bupivacaine + 0.5 m

Eligibility

Inclusion criteria

Inclusion criteria: 1. American Society of Anaesthesiologists (ASA) physical status I and II. 2. 18- 65 years of age. 3. Either sex

Exclusion criteria

Exclusion criteria: 1. History of allergy to study drugs 2. Bleeding disorder 3. Local site infection 4. Cardiac,respiratory and kidney disorder,neurological deficit 5.Spinal deformity

Design outcomes

Primary

Measure	Time frame
To compare the duration of postoperative Analgesia (demand of first rescue analgesia)in first 24 hoursTimepoint: Outcome will be assessed at 24 hours post-op	—

Secondary

Measure	Time frame
1. Hemodynamic parameters- Heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), oxygen saturation (spo2) 2. Adverse effects.Timepoint: Outcome will be assessed at baseline 2min intra-op 4min intra-op 6min intra-op 8min intra-op 10min intra-op then every 5 min after 10 min intraoperatively & for 24 hour period post op to see any adverse effect	—

Measure

Time frame

1. Hemodynamic parameters- Heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), oxygen saturation (spo2) 2. Adverse effects.Timepoint: Outcome will be assessed at baseline 2min intra-op 4min intra-op 6min intra-op 8min intra-op 10min intra-op then every 5 min after 10 min intraoperatively & for 24 hour period post op to see any adverse effect

—

Countries

India

Contacts

Public ContactDr Yumnam Arunkumar Singh

Regional Institute of Medical Sciences, Imphal, Manipur

drmram6@gmail.com8259055986

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026