Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Magnesium sulfate: injection Magnesium sulfate 30 mg/kg body weight will be given in intravenous route once before intubation. The drug should be given slowly over 30 second.
Control In
Sponsors
Department of Anaesthesiology
Eligibility
Inclusion criteria
Inclusion criteria: 1.American Society of Anesthesiologists (ASA) grade I & II. 2.Patients undergoing Elective laparoscopic cholecystectomy under GA 3.Patietns who have given informed consent
Exclusion criteria
Exclusion criteria: 1.patients having uncontrolled systemic disease 2. patients undergoing emergency surgery 3. patients having known allergy to the drugs used 4.Patient with hypersensitivity to any of the research drugs 5.Patients undergone clinical trial within 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the laryngoscopic stress response (Systolic Blood Pressure) attenuation by using iv fentanyl and iv magnesium sulphate as premedication in patients undergoing laparoscopic cholecystectomy under general anesthesia .Timepoint: Hemodynamic parameters will be noted in means of systolic blood pressure after giving premedication,just after induction,immediately after laryngoscopy, 2 minutes post intubation,5 minute after intubation. | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare Heart Rate changes during Laryngoscopy between two groupsTimepoint: Intraoperative period;To compare requirement of intravenous induction agent Propofol among two groups.Timepoint: Intraoperative period;To compare the side effects of the two adjuvants used (if any)Timepoint: Intraoperative & postoperative period upto 12 hours | — |
Countries
India
Contacts
Public ContactProfessor Subrata Kumar Mandal
College of Medicine and Sagore Dutta hospital
Outcome results
None listed