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Does Leukotriene receptor antagonists improve outcomes of patients with allergic fungal rhinosinusitis.

Role of Leukotriene Receptor Antagonists in the Postoperative Management of Allergic Fungal Rhinosinusitis. A Prospective Randomized Controlled Trial. - MONT-AFS TRIAL

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/02/062794
Enrollment
44
Registered
2024-02-19
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J309- Allergic rhinitis, unspecified Health Condition 2: J324- Chronic pansinusitis Health Condition 3: J310- Chronic rhinitis Health Condition 4: J399- Disease of upper respiratory tract, unspecified Health Condition 5: J308- Other allergic rhinitis Health Condition 6: J328- Other chronic sinusitis Health Condition 7: J338- Other polyp of sinus Health Condition 8: J348- Other specified disorders of noseand nasal sinuses Health Condition 9: J393- Upper respiratory tract hyper

Interventions

Intervention1: MONTELUKAST: Tablet Montelukast 10mg one tablet Once orally at bedtime for 3 months Control Intervention1: NOT APPLICABLE: NOT APPLICABLE Control Intervention2: NIL INTERVENTION: NIL IN

Sponsors

Christian Medical College Vellore
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ADULTS AGED MORE THAN 18 YEARS - MALE AND FEMALE PATIENTS DIAGNOSED WITH ALLERGIC FUNGAL RHINOSINUSITIS

Exclusion criteria

Exclusion criteria: CHILDREN LESS THAN 18 YEARS PREGNANT WOMEN PATIENT WITH CONTRAINDICATIONS TO MONTELUKAST PATIENT NOT GIVING CONSENT

Design outcomes

Primary

MeasureTime frame
1. Subjective scores – SNOT 22, VAS 2. Objective scores - Lund Kennedy endoscopic gradingTimepoint: 3 MONTHS

Secondary

MeasureTime frame
1. Skin Allergy Testing for fungal allergensTimepoint: 3 MONTHS

Countries

India

Contacts

Public ContactDr. Rebecca Mridula Singh

Christian Medical College, Vellore

regikurien@cmcvellore.ac.in9655806300

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026