Study of intermittent fasting to check whether it can cause weight loss improve liver function and quality of life and normalise blood pressure in fatty liver patients when compared to those not following intermittent fasting

To compare the weight loss Liver function tests blood pressure and quality of life in patients of metabolic syndrome and or NAFLD with and without Time restricted eating an open label interventional study - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/02/062783

Enrollment

193

Registered

2024-02-19

Start date

Unknown

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E660- Obesity due to excess calories

Interventions

Intervention1: Time restricted eating: The test group will be advised time-restricted eating for 14 hours by fixing a feeding window of 9 am to 7 pm to ensure 14 hours of fasting and gradually reducin

Eligibility

Inclusion criteria

Inclusion criteria: Diagnosed case of metabolic syndrome and or Nonalcoholic fatty liver disease Age between 18 and 75 years Body mass index of greater than or equal to 25 kilogram per metre square

Exclusion criteria

Exclusion criteria: Pregnancy or lactation Inherited or acquired immunodeficiency On immunosuppressive drugs On insulin or insulin secretagogues Malignancies Mental illness Chronic kidney disease with estimated glomerular filtration rate eGFR less than or equal to30 Aspartate aminotransferase or Alanine transaminase more than three times the upper limit of normal

Design outcomes

Primary

Measure	Time frame
Liver function tests at baseline and at 12 weeksTimepoint: Liver function tests at baseline and at 12 weeks	—

Secondary

Measure	Time frame
weight loss in terms of Body Mass IndexTimepoint: At baseline and after 3 months;Fasting lipid profileTimepoint: At baseline and after 3 months;mean blood pressureTimepoint: At baseline and after 3 months;quality of life through a questionnaire of patients included in the study QOL will be assessed using the WHO BREF questionnaire.Timepoint: At baseline and after 3 months	—

Countries

India

Contacts

Public ContactDr Simi Bridjit Gomaz

All India institute of medical sciences jodhpur

sidhurimple@yahoo.com9784525975

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026