FindTrial
Sign In

Comparison of two reversal agents (Sugammadex and Neostigmine) for spine surgery in adult patient under general anaesthesia

Comparative evaluation of sugammadex and neostigmine as reversal agent for spine surgery in adult patients: A randomised double blind, comparative study. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/02/062776
Enrollment
62
Registered
2024-02-16
Start date
Unknown
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S124- Fracture of fifth cervical vertebra Health Condition 2: S120- Fracture of first cervical vertebra Health Condition 3: S123- Fracture of fourth cervical vertebra Health Condition 4: S320- Fracture of lumbar vertebra Health Condition 5: S121- Fracture of second cervical vertebra Health Condition 6: S126- Fracture of seventh cervical vertebra Health Condition 7: S125- Fracture of sixth cervical vertebra Health Condition 8: S122- Fracture of third cervical vertebra Health C

Interventions

Intervention1: Reversal after neuromuscular blockade in spine surgery: Comparison of two reversal agent for the first 30 to 45 minutes after completion of spine surgery under general anaesthesia Contr

Sponsors

Department of Anaesthesiology RNT Medical college and MB Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patient physical status ASA 1,2,3 2. Posted for spine surgery under general anaesthesia

Exclusion criteria

Exclusion criteria: 1. Neuromuscular diseases 2. A history of malignant hyperthermia 3. Significant renal dysfunction 4. Refusal to sign consent 5. Patients exposed to general anaesthesia in the preceding 7 days before study

Design outcomes

Primary

MeasureTime frame
To evaluate and compare the time required and quality of emergence from neuromuscular blockade using sugammadex versus neostigmineTimepoint: up to 30 minutes post operatively—

Secondary

MeasureTime frame
1. Haemodynamic changes 2. Recovery profile 3. Patient satisfaction score 4. Side effectsTimepoint: Up to 24 hours post operatively—

Countries

India

Contacts

Public ContactDr Aman Azad

RNT Medical college and MB hospital

Khemraj10@gmail.com9414759782

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026