Skip to content

Effect of Exercise on Age related muscle weakness among People with Type 2 diabetes mellitus

Effect of Exercise-based Intervention on Mitochondrial Dysfunction in Type 2 Diabetes Mellitus with Sarcopenia- A Randomized Controlled Trial - Nil

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/02/062765
Enrollment
224
Registered
2024-02-16
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E116- Type 2 diabetes mellitus with other specified complications

Interventions

Intervention1: Exercise-based Intervention: Exercise-based intervention will be administered for 12 weeks which will mainly target on muscle strength, muscle mass and improving quality of life. It con

Sponsors

ICMR Extramural Research Programme Investigator Initiated Projects Intermediate Grant
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age between 40-70 years Individuals diagnosed with T2DM and on medication SARC-F score more than or equal to 4 Less than 600 MET minutes per week

Exclusion criteria

Exclusion criteria: History of lower limb amputation and lower limb injury Active lower limb ulcer Neuromuscular pathology Any Neurodegenerative diseases Any Cardiac disorders Patients diagnosed with Cancer Systemic illness which hinders participation in the study

Design outcomes

Primary

MeasureTime frame
SARC F Questionairre Hand Grip Strength using Jamar Hand held Hydraulic Dynamometer Quadriceps and Calf muscle circumference using Inch tape Skeletal mass index using BIA- Inbody 270Timepoint: Baseline 12th week of intervention 24th week

Secondary

MeasureTime frame
Muscle ultrasound imaging of Quadriceps and Calf muscles Blood Biomarkers Timed Up and Go testTimepoint: Baseline 12th week of intervention 24th week

Countries

India

Contacts

Public ContactDr G Arun Maiya

Manipal College of Health Professions, Manipal Academy of Higher Education

dee.shettigar@gmail.com9620886655

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026