To compare the two drugs - one applied on the skin and the other given in the vein - in post operative pain management in patients who underwent Laparoscpoic Appendicectomy

To compare efficacy of transdermal Diclofenac (Nu Patch 200mg) with conventional analgesia in post operative pain management after Laparoscopic Appendicectomy - a Randomised Control Trial - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/02/062761

Enrollment

112

Registered

2024-02-16

Start date

Unknown

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K358- Other and unspecified acute appendicitis

Interventions

Intervention1: Diclofenac: Transdermal Diclofenac Patch containing 200mg Diclofenac has to be used for post operative pain management in patients undergoing Laparoscopic Appendicectomy. Route of admin

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients undergoing laparoscopic appendicectomy with 3 ports (two ports of 10mm at periumbilical region and Suprapubic region and one of 5mm at left iliac fossa) 2. Patients more than 18 years and equal to or less than 40 years 3. Patients with no comorbid condition 4. Patients who are willing to participate in the study.

Exclusion criteria

Exclusion criteria: 1. Laparoscopic converted to open procedure 2. Patients allergic to Diclofenac or any other NSAIDS 3. Difference in number and location of port sites 4. Patients less than 18 years and more than 40 years 5. Patients with comorbid conditions 6. Patients with appendicular mass/abscess/peritonitis 7. Patients with renal diseases 8. Patients with associated conditions like- pelvic abscess/collection, Meckel’s diverticulitis, pelvic inflammatory disease, any other pelvic condition.

Design outcomes

Primary

Measure	Time frame
Postoperative pain management for 1 dayTimepoint: 1 day	—

Secondary

Measure	Time frame
Post Operative pain management for 2-3 daysTimepoint: 2-3 days	—

Countries

India

Contacts

Public ContactRhythm Uppal

Jawaharlal Nehru Medical College, Nehru Nagar, Belagavi

hombalp@yahoo.com6364506981

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026