Comparison between two drugs for surgery under spinal anesthesia

Comparison between Dexmedetomidine and Buprenorphine as an adjuvants to Levobupivacaine in patients undergoing surgery under spinal anesthesia - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/02/062754

Enrollment

Registered

2024-02-16

Start date

Unknown

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: R688- Other general symptoms and signs

Interventions

Intervention1: Buprenorphine: Patients shall receive 3 ml of 0.5% Levobupivacaine (heavy) + 0.5ml (150mcg) Buprenorphine intrathecally Intervention2: Dexmed

Eligibility

Inclusion criteria

Inclusion criteria: patient undergoing lower limb surgeries ASA physical status 1 and 2

Exclusion criteria

Exclusion criteria: patient having local pathology at the site of intrathecal block patient with coagulation disorder history of known sensitivity to study drugs

Design outcomes

Primary

Measure	Time frame
The study shall help determine which of the two combinations is better in providing prolonged and uninterrupted post operative analgesiaTimepoint: The hemodynamic parameters (HR, NIBP, MAP) and Oxygen Saturation (SpO2) shall be recorded at Baseline, 3,10, 15, 30, 45, 60, 75, 95, 110, 125, 150, 180 minutes	—

Secondary

Measure	Time frame
to study side effects & hemodyanamic changesTimepoint: VAS Score shall be recorded at two hourly for first 6 hour & then four hourly in a 24 hour assessment period.	—

Countries

India

Contacts

Public ContactShadab Hussain

Eras Lucknow Medical College and Hospital

shadabamul@gmail.com8861191318

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026