Health Condition 1: K859- Acute pancreatitis, unspecified
Conditions
Interventions
Intervention1: Simultaneous Strategy: In simultaneous approach, all measures will be taken upfront within 24 hours of randomization to decrease IAP, viz., Ryle’s tube and flatus tube insertion, neosti
Sponsors
Dr. Jayanta samanta
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patient’s age = 18 years 2. Informed consent for participation in the study 3. All patients of acute pancreatitis presenting within 14 days of pain onset. 4. Presence of intra-abdominal hypertension as per the definition
Exclusion criteria
Exclusion criteria: History of arrhythmia Bronchial asthma pregnancy history of laparotomy prior endoscopic/radiological/surgical intervention lack of informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. The percentage difference in the reduction of IAP at 72 hrs between step up approach and simultaneous approach for management of IAH 2. Composite outcome parameter of mortality, surgery, need for ventilator and development of new onset multiple organ failureTimepoint: 1. At the end of 72 hrs of intervention 2. At the end of the index hospital admission | — |
Secondary
| Measure | Time frame |
|---|---|
| a. Resolution of organ failure b. Duration of organ failure c. Development of infected pancreatic necrosis or other infective complications d. Length of hospital stay and ICU stay e. Need for organ support in the form of ventilator requirement, renal replacemnet therapy f. Need for surgery g. MortalityTimepoint: At the end of the index hospital admission | — |
Countries
India
Contacts
Public ContactDr Purnima Patial
PGIMER Chandigarh India
Outcome results
None listed