Health Condition 1: K053- Chronic periodontitis
Conditions
Interventions
Intervention1: Vaspin Biomarker with Local drug delivery (Tetracycline fibres-Periodontal Plus Ab): Evaluation of Vaspin biomarker in patients after non surgical periodontal therapy with Local drug de
Sponsors
Cynthia Leslie C
Eligibility
Inclusion criteria
Inclusion criteria: a. Individuals aged from 25 to 70 years will be included. b. Patients with type 2 diabetes were included if they presented with a history of type 2 DM for the past 1 year or more and treated with oral hypoglycemic drugs (Dog?an et al., 2016). The glycemic status was evaluated using HbA1c, based on the American Diabetic Association classification 2021 for diagnosis of type 2 diabetes. c. Patient with generalized Chronic Periodontitis, exhibiting probing pocket depth of =4mm and clinical attachment level (CAL) of =3mm in more than 30% of diseased sites with a minimum of 15 teeth (according to the American Academy of Periodontology 2018 World Workshop classification of periodontal diseases).
Exclusion criteria
Exclusion criteria: a. Systemic conditions influencing the course of periodontal disease other than type 2 diabetes. b. Patients with a history of periodontal treatment within the previous 6 months. c. Patients under antimicrobial therapy, immunosuppressant, or anti-inflammatory drugs within the past 3 months. d. Patients with habit of smoking and alcoholism. e. Pregnant and lactating women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Salivary Vaspin levels in Patients with Chronic Periodontitis with and without Type II Diabetes Mellitus.Timepoint: At baseline and 1 month (4 weeks) after Non surgical periodontal therapy | — |
Secondary
| Measure | Time frame |
|---|---|
| Assessment of HbA1c levels of patientsTimepoint: Before and after Non surgical periodontal therapy | — |
Countries
India
Contacts
Public ContactCynthia LeslieC
Chettinad Dental College and Research Institute
Outcome results
None listed