To study if brain training helps in depression

To study the effect of neurofeedback training on depression scores and prefrontal cortical activity in depression: a randomized control study - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/02/062695

Enrollment

Registered

2024-02-15

Start date

Unknown

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F330- Major depressive disorder, recurrent, mild Health Condition 2: F331- Major depressive disorder, recurrent, moderate Health Condition 3: F320- Major depressive disorder, singleepisode, mild Health Condition 4: F321- Major depressive disorder, singleepisode, moderate

Interventions

Intervention1: Neurofeedback training: Patients diagnosed with depression attending Psychiatry OPD of AIIMS,Nagpur who satisfy the inclusion and exclusion criteria will be included.The patient will be

Eligibility

Inclusion criteria

Inclusion criteria: Age 18-55 years both genders, Diagnosis according to ICD 10 by psychiatrist, HDRS score equal to or more than 8, ongoing treatment for atleast 4 weeks or more, normal or corrected to normal vision, normal colour vision assessed by ishihara chart

Exclusion criteria

Exclusion criteria: Any history secondary causes of cognitive impairment (like history of stroke, brain injury, psychosis, exposure to toxins, substance abuse, history of neurological disease, dementia, Alzheimer’s disease or any neurological illness with significant cognitive impairment). Dementia will be ruled out with MoCA score =18

Design outcomes

Primary

Measure	Time frame
To study the effect of 4-weeks of fNIRS based neurofeedback training on depression scores, resting and cognitive task based prefrontal cortical activity in depressionTimepoint: Day 1 (Baseline), Day 29 (Post intervention)	—

Secondary

Measure	Time frame
To assess whether the antidepressant effects of neurofeedback training on depression scores lasts even after 4 weeks of completion of trainingTimepoint: Depression scores on day 0 Depression scores on day 57	—

Countries

India

Contacts

Public ContactKanika

All India Institute of Medical Sciences, Nagpur

phatakms@gmail.com8826363922

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026