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Effect of various toothpastes on growth of oral bacteria in handicapped children

Comparative evaluation of effect of Xylitol and Xylitol-probiotic containing toothpastes on salivary Streptococcus mutans and Lactobacillus count in handicapped children: A Randomized Controlled Trial - Nil

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/02/062684
Enrollment
90
Registered
2024-02-15
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Z538- Procedure and treatment not carried out for other reasons

Interventions

Intervention1: Xylitol-probiotic toothpaste: Identification and quantification of oral bacterial growth with pre and post intervention samples. Children are provided with 0.25 gm of toothpaste twice a

Sponsors

Dr Sonali Devidas Lingayat
Lead Sponsor
Dr Yogesh Kale
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1.Special health care needs children in the age group of 7 to 13 years (Both males and Females). 2.Participants who had not received any antibiotic agent or professional fluoride therapy within the last month. 3.Children with active carious lesions. 4.Children willing to participate in the study.

Exclusion criteria

Exclusion criteria: 1. Individuals with habitual use of dairy probiotics or xylitol chewing gums 2. Those who have severe debilitating condition 3. Children not willing to or able to cooperate

Design outcomes

Primary

MeasureTime frame
There is an inhibitory effect of Xylitol and Xylitol-probiotic containing toothpastes on oral bacterial growthTimepoint: 6 weeks

Secondary

MeasureTime frame
Compare and evaluate the oral bacterial growth before and after using the Xylitol and Xylitol-probiotic containing toothpaste with conventional toothpasteTimepoint: 6 weeks

Countries

India

Contacts

Public ContactDr Sonali Devidas Lingayat

MIDSR Dental College, Latur, Maharashtra

sonalingayat05@gmail.com9834579082

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026