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Comparing Pain Relief Methods After Gallbladder Surgery Using Local Injections

Comparative study of analgesic efficacy of preclosure periportal infiltration with that of peritoneal infiltration of local anaesthetics for post operative analgesia in patients undergoing laparoscopic cholecystectomy-A double blind randomised prospective study - NIL

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/02/062680
Enrollment
50
Registered
2024-02-15
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K806- Calculus of gallbladder and bile duct with cholecystitis

Interventions

Intervention1: laparoscopic cholecystectomy. Bupivacaine0.25%: Group A-patients will recieve port site infiltration[local] of 20ml of 0.25% Inj Bupivacaine with 4 mg Inj Dexamethasone. Group B- patien

Sponsors

DR RANJINI SHOME
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA grades 1 and 2 of either sex. 2.Patients between age group of 20 to 60 years. 3.Undergoing elective laparoscopic cholecystectomy under General anesthesia.

Exclusion criteria

Exclusion criteria: 1. Patients with acute cholecystitis. 2. Patients allergic to drug used in the study. 3. Patients who have morbid obesity, choledocholithiasis, patients with chronic pain syndrome, previous upper abdominal surgery, chronic medical disease, chronic opiod treatment. 4. Patients requiring placement of drain postoperatively. 5 Those with stone spillage. 6.Patients in whom conversion to open cholecystectomy was done for any reason

Design outcomes

Primary

MeasureTime frame
1.To compare the analgesic efficacy of periportal and intraperitoneal infiltration of 0.25% Bupivacaine with Dexamethasone 4mg using visual analog scale. 2. to compare total analgesic consumption in first 24 hours. 3.To compare the incidence of adverse effects like shoulder pain , vomiting. 4.To compare degree of ambulation in postoperative periodTimepoint: 8 weeks

Secondary

MeasureTime frame
to compare the incidence of adverse effects like shoulder tip pain, vomiting. To compare the degree of ambulation. To compare the total analgesic comsumption in first 24 hours.Timepoint: 24 hours

Countries

India

Contacts

Public ContactDr Ranjini Shome

MGR UNIVERSITY

drashwinih@rediffmail.com8971265579

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026