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A study to compare two echocardiographic parameters-Left ventricular global longitudinal strain(LVGLS) and Left ventricular ejection fraction(LVEF) in predicting heart dysfunction in patients undergoing aortic and mitral valve replacement or repair surgeries for regurgitant diseases

COMPARITIVE STUDY OF LEFT VENTRICULAR GLOBAL LONGITUDINAL STRAIN(LVGLS) AND LEFT VENTRICULAR EJECTION FRACTION(LVEF) IN PREDICTING LOW CARDIAC OUTPUT SYNDROME(LCOS) IN PATIENTS UNDERGOING AORTIC AND MITRAL VALVE REPLACEMENT/REPAIR SURGERY FOR REGURGITANT LESIONS.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/02/062672
Enrollment
130
Registered
2024-02-15
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I080- Rheumatic disorders of both mitraland aortic valves

Interventions

Control Intervention1: NIL: NIL

Sponsors

Post Graduate Institute of Medical Education and Medical Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: PATIENTS UNDERGOING AORTIC AND MITRAL VALVE REPLACEMENT/REPAIR FOR REGURGITANT LESIONS

Exclusion criteria

Exclusion criteria: ACUTE MITRAL AND AORTIC REGURGITATION PATIENTS REQUIRING ADDITIONAL VALVULAR SURGERY LIKE TRICUSPID REPAIR/REPLACEMENT PATIENTS UNDERGOING CONCOMITANT SURGERIES LIKE CABG,AORTIC SURGERY POOR TRANSTHORACIC ECHO WINDOW

Design outcomes

Primary

MeasureTime frame
TO INVESTIGATE WHETHER LV DEFORMATION PARAMETER-GLOBAL LONGITUDINAL STRAIN (GLS)IS AB BETTER PREDICTOR OF LV DYSFUNCTION THAN LVEF IN PATIEBTS UNDERGOING VALVE REPALCEMENT/REPAIR SURGERY FOR AORTIC AND MITRAL VALVE REGURGITANT LESIONS WITH DILATED LVTimepoint: PRE INDUCTION,PRE CPB,POST CPB,POD 1,ON WEANING INOTROPES,3 MONTHS FOLLOW UP—

Secondary

MeasureTime frame
AGREEMENT BETWEEN TRANSTHORACIC AND TRANSESOPHAGEAL ECHO IN ASSESSING LVGLSTimepoint: PRE INDUCTION,PRE CPB,POST CPB,POD 1,ON WEANING INOTROPES,3 MONTHS FOLLOW UP;CORRELATE LV STRAIN PARAMETERS WITH LVEF,LVEDD,LVEDS,EPSSTimepoint: PRE INDUCTION,PRE CPB,POST CPB,POD 1,ON WEANING INOTROPES,3 MONTHS FOLLOW UP;CORRELATION BETWEEN LVGLS AND POST OP COMPLICATIONSTimepoint: PRE INDUCTION,PRE CPB,POST CPB,POD 1,ON WEANING INOTROPES,3 MONTHS FOLLOW UP;PROGNOSTIC VALUE OF GLSTimepoint: PRE INDUCTION,PRE CPB ,POST CPB,POD 1,ONM WEANING INOTROPES,3 MONTHS FOLLOW UP;TO COMPAREV DEMOGRAPHIC,CLINICAL AND INTRAOPERATIVE CHARACTERISTICSTimepoint: PRE INDUCTION,PRE CPB,POST CPB,POD 1,ON WEANING INOTROPES,3 MONTHS FOLLOW UP—

Countries

India

Contacts

Public ContactBanashree Mandal

POST GRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH

banashreemandal@yahoo.co.in8146266102

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026