Effect of Bacillus clausii in the management of acute diarrhoea in children

Comparative study on clinical efficacy of Bacillus Clausii ( Bifilac Clausi ) in the management of acute diarrhoea in children as an add on therapy with standard therapy- A randomized control study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/02/062669

Enrollment

Registered

2024-02-15

Start date

Unknown

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A084- Viral intestinal infection, unspecified

Interventions

Intervention1: Bifilac Clausi: Bacillus Clausii 2 billion CFU Intervention2: Bifilac Clausi + ORS + Zinc: Bacillus clausii 2 billion CFU for 5 days BD ORS Zinc sulphate 20 mg for 14 days Control Inter

Eligibility

Inclusion criteria

Inclusion criteria: Children aged between 6 months to 5 years old with care of diarrhoea less than 3 days

Exclusion criteria

Exclusion criteria: Children with severe dehydration Presence of systemic infections Children with known immunocompromising morbidities Children with severe acute malnutrition, Children with chronic or severe respiratory, cardiovascular, central nervous system, endocrine and other gastrointestinal disorders on clinical examination

Design outcomes

Primary

Measure	Time frame
Frequency of loose stoolsTimepoint: 24 hours and 72 hours and 120 hours	—

Secondary

Measure	Time frame
Changes in stool consistencyTimepoint: 24 hours & 72 hours & 120 hours	—

Countries

India

Contacts

Public ContactDr Aruna

Government Kilpauk Medical College

drkkarthika439@gmail.com9655516516

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026