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To compare effect of clonidine versus fentanyl as an adjuvant to isobaric ropivacaine in patient undergoing vaginal hysterectomy under spinal anaesthesia

A randomized study to compare effectiveness of clonidine VS fentanyl as an adjuvant to 0.75% isobaric ropivacaine in patient undergoing vaginal hysterectomy under spinal anaesthesia in department of anaesthesiology,SMS medical college and attached hospitals Jaipur - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/02/062640
Enrollment
60
Registered
2024-02-14
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N939- Abnormal uterine and vaginal bleeding, unspecified Health Condition 2: N00-N99- Diseases of the genitourinary system

Interventions

Intervention1: Evaluate effect of two drugs for analgesia undergoing vaginal hysterectomy under spinal anaesthesia: All hemodynamic variables i.e. SBP,DBP,MAP,PR,SPO2
total duration of sensory block,2 segments regression time,total duration of motor blockade,first rescue analgesia will be checked . Control Intervention1: To evaluate Effect of clonidine as adjuvant

Sponsors

Department of anaesthesiology SMS Medical college and hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Willing for study and has given informed and written consent,undergoing vaginal hysterectomy,ASA grade II,body weight 40 to 70 kg,height more than 145cm.

Exclusion criteria

Exclusion criteria: Patient should not be a part of other study,non co operative patient,history of allergy and hypersensitivity to any drug of study,any deformity or local sepsis in spinal lumbar region,severe hypovolemia,any bleeding or coagulation abnormalities,patients receiving CNS depressants,any major co morbidity such as COPD,NEUROLOGICAL,CARDIOVASCULAR,METABOLIC,HEPATIC,RESPIRATORY OR RENAL DISEASE.

Design outcomes

Primary

MeasureTime frame
Mean time duration of first rescue analgesia,number of rescue analgesia during 24 hours post operative period,mean time for onset of sensory and motor block,mean time duration of sensory and motor block.mean of hemodynamic parameters at various intervals,proportion of cases with side effects.Timepoint: At 1,2,3,5,10,15,20,25,30,40,50,60 minutes

Secondary

MeasureTime frame
NilTimepoint: Nil

Countries

India

Contacts

Public ContactDr Sanjay Verma

SMS MEDICAL COLLEGE, JAIPUR

sanjay85.sv@gmail.com9785698694

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026