Comparative evaluation of efficiency of Neem mouthwash versus Dexamethasone mouthwash in management of oral submucous fibrosis: A Randomized clinical trial

Comparative evaluation of efficacy of neem mouthwash versus dexamethasone mouthwash as an adjuvant in the symptomatic management of oral submucous fibrosis: A randomized clinical trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/02/062636

Enrollment

Registered

2024-02-14

Start date

Unknown

Completion date

Unknown

Last updated

2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: K135- Oral submucous fibrosis

Interventions

Intervention1: NEEM MOUTH WASH: 10ML DILUTED WITH 10ML OF WATER 2 times daily for 1 week Control Intervention1: DEXAMETHASONE MOUTH WASH: 0.5MG DEXAMETHASONE TABLET IN 20ML OF WATER 2 times daily for

Eligibility

Inclusion criteria

Inclusion criteria: 1 PATIENTS ABOVE THE AGE OF 18 YEARS CLINICALLY DIAGNOSED WITH ORAL SUBMUCOUS FIBROSIS. 2 PATIENTS WILLING TO PATICIPATE IN THE STUDY. 3 PATIENTS WILLING TO QUIT THE HABIT AS INSTRUCTED.

Exclusion criteria

Exclusion criteria: 1 PATIENTS WHO ARE ALREADY UNDERGOING TREATMENT FOR ORAL SUBMUCOUS FIBROSIS. 2 PATIENTS WITH TMJ PROBLEMS, PERICORONITIS OF LOWER THIRD MOLARS ETC,WHICH MAY CAUSE REDUCED MOUTH OPENING. 3 PATIENTS WITH PAST HISTORY OF TB.

Design outcomes

Primary

Measure	Time frame
THERE WILL BE REDUCTION IN BURNING SENSATION OF MOUTH.Timepoint: 1 week	—

Secondary

Measure	Time frame
THERE WILL BE INCREASE IN INTERINCISAL MOUTH OPENINGTimepoint: 1 WEEK	—

Countries

India

Contacts

Public ContactPOKURU APARNA

NARAYANA DENTAL COLLEGE & HOSPITAL

rmannae@rediffmail.com8179805938

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026