Health Condition 1: F20- Schizophrenia
Conditions
Interventions
Intervention1: High-definition Transcranial Direct Current Stimulation primed Intensive Cerebellar Intermittent Theta Burst Stimulation: Patients will receive 10 sessions of transcranial direct curren
Sponsors
Shri Guru Ram Rai Institute of Medical and Health Sciences
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with a diagnosis of Schizophrenia based on diagnostic criteria of Diagnostic and Statistical Manual of Mental Disorder, 5th edition 2. Patients aged 18-59 years 3. Patients giving written consent to participate in protocol 4. Patients fulfilling criteria of Treatment resistant schizophrenia according to Modified Kane’s criteria
Exclusion criteria
Exclusion criteria: 1. Patient is uncooperative for procedure 2. Active substance use disorder(except caffeine and tobacco) or any other current psychiatric comorbidity 3. Implanted metal or cerebral devices in head and neck 4. History of unprovoked seizures, intracranial neoplasms or intracranial surgery, or history of severe head injury or cerebrovascular disease 5. Patients having significant unstable medical condition like uncontrolled hypertension, complicated diabetes mellitus, etc 6. Patients receiving ECT in last 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess and compare symptoms of schizophrenia in patients of treatment resistant schizophrenia following high definition transcranial direct current stimulation primed intensive cerebellar intermittent theta burst stimulation in active and sham groupTimepoint: Baseline PANSS, BPRS, SCoRS, SAS and CGI will be applied on day 0, 7 and 14 | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess cognitionTimepoint: SCoRS applied on day 0,7 and 14 | — |
Countries
India
Contacts
Public ContactDr Abhishri Ranjan
Sri Guru Ram Rai Institute of Medical and Health Sciences
Outcome results
None listed