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Clinical outcomes of locally advanced oral cavity cancers treated with definitive radiotherapy by VMAT technique

Clinical outcomes of locally advanced oral cavity cancers treated with definitive volumetric modulated radiotherapy - A prospective single center study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/02/062620
Enrollment
33
Registered
2024-02-14
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx

Interventions

Control Intervention1: NIL: NIL

Sponsors

Sri venkateswara institute of medical science
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Histo-pathologically proven squamous cell carcinoma [SCC] of lips, buccal mucosa, tongue, gingiva, hard palate, retro molar trigone, floor of mouth. 2. Age : 18 -70 years . 3. Patients with eastern cooperative oncology group [ECOG] performance status of 0-2 . 4. Stage III to IVb SCC of oral cavity [american joint committee on cancer : 8th edition]. 5. Patients with stage III to IVb SCC of oral cavity, not willing for surgery.

Exclusion criteria

Exclusion criteria: 1. Cancer with distant metastasis. 2. Patient with ECOG performance status of 3-4. 3. Patients who have undergone surgery. 4. Patients previously treated with radiotherapy to head & neck region. 5. Pregnant and lactating mothers.

Design outcomes

Primary

MeasureTime frame
To estimate TUMOR RESPONSE in locally advanced oral cavity cancers treated by volumetric modulated arc radiotherapy with curative intentTimepoint: 3 months post radiotherapy—

Secondary

MeasureTime frame
• ACUTE TOXICITIES- • Mucositis • Dermatitis • Dysphagia • Xerostomia Timepoint: Weekly during radiotherapy and monthly up to 3 months post radiotherapy;• LATE TOXICITIES- • Dysphagia • Xerostomia • Dermatitis • Mucositis Timepoint: Every 3 monthly up to 1 year post radiotherapy—

Countries

India

Contacts

Public ContactDr Pranabandhu das

SVIMS TIRUPATI

drpranabandhu79@gmail.com9493547731

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026