Health Condition 1: N800- Endometriosis of uterus
Conditions
Interventions
Intervention1: Dienogest: 12-week course of cyclic regimen of Dienogest is given to all participant (21 days with 2 mg of dienogest starting on the first day of menstrual cycle followed by 7 drug free
Sponsors
Songklanagarind hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1.Adenomyosis is diagnosed by ultrasound 2.Dysmenorrhea with visual analog scale more than 3 3.Woman with regular frequency of menstruation 24-38 days for 3 cycles 4.No pregnancy desire during the treatment and trial period 5.No co-existing endometrioma or myoma or current PID by pelvic examination and ultrasonography
Exclusion criteria
Exclusion criteria: 1.Contraindication of dienogest 2.Previous hormonal treatment within 3 months or current use 3.History or suspicious of gynecologic malignancy or hormonal responsive tumor 4.Currently breastfeeding 5.Current use of drugs with interaction to cytochrome P450
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the change in visual analog scale (VAS) of dysmenorrhea during treatment women diagnosed with adenomyosis by cyclic regimen of dienogestTimepoint: 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate adverse effect of cyclic regimen of dienogest.Timepoint: 3 months;To evaluate patterns and amount of uterine bleeding during treatment with cyclic regimen of dienogest.Timepoint: 3 months | — |
Countries
Thailand
Contacts
Public ContactPakhanan Dankamak
Prince of Songklha University
Outcome results
None listed