Health Condition 1: C50- Malignant neoplasm of breast
Conditions
Interventions
Intervention1: Gabapentin, Dexamethasone, Paracetamol, Ketorolac: Tab. Gabapentin 600mg orally and intravenous dexamethasone 0.2mg/kg will be given 1 hr before surgery. Intravenous paracetamol 1gm an
Sponsors
Parin Lalwani
Eligibility
Inclusion criteria
Inclusion criteria: Patients of ASA physical status I and II posted for elective Modified Radical Mastectomy
Exclusion criteria
Exclusion criteria: 1. Patient refusal 2. Known allergy to the drug 3. H /O gastric or duodenal ulcer 4. H/O Asthma 5. H/O Diabetes mellitus 6. Pregnancy 7. Chronic analgesic or steroid or opioid consumption 8. Patient who is already on gabapentin or any other antiepileptic drugs or antidepressant or benzodiazepines 9. Impaired kidney and liver function 10. BMI >30 11. Limitations in understanding use of PCA pump 12. H/O Migraine or Chronic Pain
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total Intravenous Patient Controlled Analgesia (PCA) fentanyl consumption in the first 24 hours postoperatively.Timepoint: 24 hours postoperatively. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Time for first analgesic requirement 2) Post operative pain scores at rest & during movement 0 min, 15 min, 30 mins, 1, 2, 4, 8, 12 and 24h 3) PONV 4) Wound healing/ infection at 1 weekTimepoint: 1) 24 hours postoperatively 2) 0 min, 15 min, 30 mins, 1, 2, 4, 8, 12 & 24hours 3) 0 min, 15 min, 30 mins, 1, 2, 4, 8, 12 and 24hours 4) 7 days postoperatively | — |
Countries
India
Contacts
Public ContactMaheshwaran S
All India Institute of Medical Sciences
Outcome results
None listed