The effect of ondansetron which is a drug used to treat vomiting, on spinal anaesthesia induced fall in blood pressure.

Effect of ondansetron on spinal anesthesia induced hypotension - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/02/062601

Enrollment

150

Registered

2024-02-13

Start date

Unknown

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Ondansetron: Single shot ondansetron will be give ten minutes before spinal anesthesia at a dose of 0.1mg/kg maximum of eight milligram intravenously. Control Intervention1: Normal sali

Eligibility

Inclusion criteria

Inclusion criteria: ASA physical status 1 to 3

Exclusion criteria

Exclusion criteria: 1.Contraindication or a history of hypersensitivity to ONDANSETRON 2.Obstretric surgeries 3.Uncontrolled hypertension 4.Localized infection at the puncture site and patients with coagulopathies.

Design outcomes

Primary

Measure	Time frame
To compare the incidence of hypotension (fall in mean arterial pressure more than 20% in the baseline values) between test and control groups.Timepoint: Immediately after spinal, at 5 min, 10 min, 15 min,30 min and every 30 min till end of surgery	—

Secondary

Measure	Time frame
To find the recquirement for inotrops to treat hypotension To find the usage of atropine and glycopyrrolate to treat bradycardiaTimepoint: Before spinal after spinal,1 min after spinal 3 minutes after spinal,5 minutes after spinal ,10minutes after spinal,15 mintues after spinal 30mintues after spinal,every 30 min till surgery ends.	—

Countries

India

Contacts

Public ContactFazil H

Amrita Institute of Medical Sciences

rajgokulam70@gmail.com9847162134

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026