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Research on the conversion of cotinine back into nicotine in human plasma

Investigation of the mechanism and enzyme responsible for the conversion of cotinine back to nicotine using human plasma - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/02/062598
Enrollment
168
Registered
2024-02-13
Start date
Unknown
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Control Intervention1: NIL: NIL

Sponsors

Sri Ramachandra Institute of Higher Education and Research DU
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Chronic smoker 2. patients above 18 years old 3. consumer of other tobacco products such as chewed products, electronic cigarette, etc.

Exclusion criteria

Exclusion criteria: 1. Patients with no smoking effect 2. Pregnant women 3. Patients taken alcohol within 24 hours

Design outcomes

Primary

MeasureTime frame
The study will estimate and compare the plasma levels of SOD,CAT,GPx in smokers and non somokersTimepoint: 6 months—

Secondary

MeasureTime frame
mechanism of the conversion of cotinine back to nicotine in presence of ascrobic acidTimepoint: 6 months—

Countries

India

Contacts

Public ContactBalamurugan S

Sri Ramachandra Institute of Higher Education and Research, Chennai-600116

murugesan.a@sriramachandra.edu.in8870151588

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026