Assessment of wound healing in periodontal flaps closed using N-Hexyl cyanoacrylate and Isoamyl 2-cyanoacrylate glue

Comparative evaluation of wound healing in periodontal flaps approximated with N-hexyl cyanoacrylate and Isoamyl 2-cyanoacrylate tissue adhesives – A clinico-histological study. - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/02/062586

Enrollment

Registered

2024-02-13

Start date

Unknown

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: N-hexyl cynoacrylate tissue adhesive: Periodontal flap approximation after periodontal flap surgery for 7 days Intervention2: Isoamyl 2-cynoacrylate tissue adhesive: Periodontal flap ap

Eligibility

Inclusion criteria

Inclusion criteria: Chronic periodontitis subjects indicated for periodontal flap surgery.

Exclusion criteria

Exclusion criteria: 1. Subjects with any pre-existing pathology. 2. Subjects with systemic diseases which delays the healing, cardiovascular diseases, poorly controlled diabetes, HIV, cancer, haemorrhagic disorders. 3. Subjects having history of drug allergy, food allergy or allergy to polymers in cyanoacrylate, glues, tissue adhesives. 4. Pregnant or lactating women. 5. Subjects using tobacco (In any form). 6. Chronic use of antimicrobial, ant-inflammatory drugs and other medications 6 months prior to the study.

Design outcomes

Primary

Measure	Time frame
1. Wound healing index (Landry, Turnbull, and Howley index) 2. Pain score (Visual Analogue Scale) 3. Plaque indexTimepoint: 7th day, 15th day, 1 month follow-up	—

Secondary

Measure	Time frame
Histological examinationTimepoint: 7th day	—

Countries

India

Contacts

Public ContactYogita Uttam Landge

YCMM and RDFs Dental Collage and Hospital Ahmednagar

drmoolya@gmail.com9987004390

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026