Comparison between different modalities of oxygen support after extubation in critically ill patients who are at high risk of extubation failure

Comparison of effects of post extubation non invasive ventilation with passive humidification and high flow nasal canula in patients with high risk of extubation failure - nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/02/062564

Enrollment

150

Registered

2024-02-13

Start date

Unknown

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R098- Other specified symptoms and signsinvolving the circulatory and respiratory systems

Interventions

Intervention1: Non invasive ventilation with passive humidification: post extubation non invasive ventilation with passive humidification in patients who are at risk of extubation failure Intervention

Eligibility

Inclusion criteria

Inclusion criteria: critically ill patients who are at high risk of extubation failure

Exclusion criteria

Exclusion criteria: Patient who dont give consent for part of study , Do not resuscitate orders, Tracheostomised patients, Age less than 18years, Accidental or self extubation , Do not reintubate orders Contraindication for NIV therapy

Design outcomes

Primary

Measure	Time frame
Reintubation within 48 hours of extubationTimepoint: 48hrs	—

Secondary

Measure	Time frame
Postextubation respiratory failure within 7 days of extubation Respiratory infection(ventilator associated pneumonia ) Sepsis or multiple organ failure, ICU length of stay Hospital length of stay ICU mortality and Hospital mortalityTimepoint: 7days	—

Countries

India

Contacts

Public ContactDr Nimisha Sudhir Patil

Era Lucknow Medical college and hospital

Dr_mall_79@yahoo.co.in9140283488

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026